{"id":240,"date":"2021-06-30T15:15:11","date_gmt":"2021-06-30T15:15:11","guid":{"rendered":"https:\/\/mims.parabolasolution.com\/?page_id=240"},"modified":"2026-04-01T14:44:29","modified_gmt":"2026-04-01T06:44:29","slug":"instructions-for-infusion","status":"publish","type":"page","link":"https:\/\/bms.mimsit.net\/dosing\/1l-msi-h-d-mmr-metastatic-recurrent-crc\/instructions-for-infusion\/","title":{"rendered":"Instructions for infusion"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"240\" class=\"elementor elementor-240\" data-elementor-settings=\"[]\">\n\t\t\t\t\t\t\t<div class=\"elementor-section-wrap\">\n\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-23d767a7 elementor-section-full_width elementor-section-height-default elementor-section-height-default\" data-id=\"23d767a7\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-68f7e703\" data-id=\"68f7e703\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1bcb3a42 elementor-widget elementor-widget-text-editor\" data-id=\"1bcb3a42\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.5.5 - 03-02-2022 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#818a91;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#818a91;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<table class=\"table table-border table-sm table-infusion\"><thead><tr><th class=\"w-25\">\u00a0<\/th><th class=\"w-25 text-center\">Nivolumab<\/th><th class=\"w-25 text-center\">Ipilimumab<\/th><\/tr><\/thead><tbody><tr class=\"table-infusion-row1\"><td class=\"align-middle p-3\"><div class=\"d-none d-lg-block\"><img decoding=\"async\" src=\"http:\/\/bms.mimsit.net\/dosing\/wp-content\/uploads\/2021\/06\/icon_b_iv.png\" width=\"70px\" \/> <span class=\"table-infusion-th\">Reconstitution<\/span><\/div><div class=\"d-block d-lg-none\"><p><img decoding=\"async\" src=\"http:\/\/bms.mimsit.net\/dosing\/wp-content\/uploads\/2021\/06\/icon_b_iv.png\" width=\"70px\" \/><\/p><p class=\"table-infusion-th\">Reconstitution<\/p><\/div><\/td><td class=\"align-middle\" colspan=\"2\">Dilute the required volume of nivolumab or ipilimumab with the required volume of 0.9% sodium chloride solution or 5% glucose solution for injection<sup>1<\/sup><\/td><\/tr><tr class=\"table-infusion-row2\"><td class=\"align-middle p-3\"><div class=\"d-none d-lg-block\"><img decoding=\"async\" src=\"http:\/\/bms.mimsit.net\/dosing\/wp-content\/uploads\/2021\/06\/icon_b_notepad.png\" width=\"70px\" \/> <span class=\"table-infusion-th\">Duration of infusion<\/span><\/div><div class=\"d-block d-lg-none\"><p><img decoding=\"async\" src=\"http:\/\/bms.mimsit.net\/dosing\/wp-content\/uploads\/2021\/06\/icon_b_notepad.png\" width=\"70px\" \/><\/p><p class=\"table-infusion-th\">Duration of infusion<\/p><\/div><\/td><td class=\"text-center align-middle\">30-min IV infusion<sup>1<\/sup><\/td><td class=\"text-center align-middle\">30-min IV infusion<sup>1<\/sup><\/td><\/tr><tr class=\"table-infusion-row1\"><td class=\"align-middle p-3\"><div class=\"d-none d-lg-block\"><img decoding=\"async\" src=\"http:\/\/bms.mimsit.net\/dosing\/wp-content\/uploads\/2021\/06\/icon_b_timer.png\" width=\"70px\" \/> <span class=\"table-infusion-th\">Order of infusion<\/span><\/div><div class=\"d-block d-lg-none\"><p><img decoding=\"async\" src=\"http:\/\/bms.mimsit.net\/dosing\/wp-content\/uploads\/2021\/06\/icon_b_timer.png\" width=\"70px\" \/><\/p><p class=\"table-infusion-th\">Order of infusion<\/p><\/div><\/td><td class=\"align-middle\" colspan=\"2\">For combination therapy, nivolumab and ipilimumab should be administered on the same day.<sup>1<\/sup>\u00a0Nivolumab infusion should be followed by ipilimumab infusion in all indications where combination therapy is indicated.<sup>1<\/sup> In all settings, nivolumab monotherapy should be initiated 3 weeks following the last dose of the combination of nivolumab and ipilimumab<sup>1<\/sup><\/td><\/tr><\/tbody><\/table>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-063689c elementor-widget elementor-widget-text-editor\" data-id=\"063689c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\tIV, intravenous.\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-c187d0b elementor-section-full_width elementor-section-height-default elementor-section-height-default\" data-id=\"c187d0b\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-da31de5\" data-id=\"da31de5\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e2aa9ff elementor-widget elementor-widget-text-editor\" data-id=\"e2aa9ff\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>1. Opdivo<sup>\u00ae<\/sup> (nivolumab). Hong Kong Prescribing Information; Hong Kong: Bristol-Myers Squibb.\u00a0<br \/>2. Yervoy<sup>\u00ae<\/sup> (ipilimumab). Hong Kong Prescribing Information; Hong Kong: Bristol-Myers Squibb.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-f4ab5d9\" data-id=\"f4ab5d9\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-cc5cebb elementor-widget__width-auto elementor-widget elementor-widget-image\" data-id=\"cc5cebb\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.5.5 - 03-02-2022 *\/\n.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=\".svg\"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block}<\/style>\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"225\" height=\"225\" src=\"https:\/\/bms.mimsit.net\/dosing\/wp-content\/uploads\/2026\/02\/qr-opdivo-feb-27-2026.png\" class=\"attachment-large size-large\" alt=\"\" srcset=\"https:\/\/bms.mimsit.net\/dosing\/wp-content\/uploads\/2026\/02\/qr-opdivo-feb-27-2026.png 225w, https:\/\/bms.mimsit.net\/dosing\/wp-content\/uploads\/2026\/02\/qr-opdivo-feb-27-2026-150x150.png 150w\" sizes=\"auto, (max-width: 225px) 100vw, 225px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6703ccb elementor-widget__width-auto elementor-widget elementor-widget-image\" data-id=\"6703ccb\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"144\" height=\"144\" src=\"https:\/\/bms.mimsit.net\/dosing\/wp-content\/uploads\/2026\/02\/qr-yervoy-feb-27-2026.png\" class=\"attachment-large size-large\" alt=\"\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>\u00a0 Nivolumab Ipilimumab Reconstitution Reconstitution Dilute the required volume of nivolumab or ipilimumab with the required volume of 0.9% sodium chloride solution or 5% glucose solution for injection1 Duration of infusion Duration of infusion 30-min IV infusion1 30-min IV infusion1 Order of infusion Order of infusion For combination therapy, nivolumab and ipilimumab should be administered [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":231,"menu_order":10,"comment_status":"closed","ping_status":"closed","template":"page-template2.php","meta":{"footnotes":""},"class_list":["post-240","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/bms.mimsit.net\/dosing\/wp-json\/wp\/v2\/pages\/240","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/bms.mimsit.net\/dosing\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/bms.mimsit.net\/dosing\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/bms.mimsit.net\/dosing\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/bms.mimsit.net\/dosing\/wp-json\/wp\/v2\/comments?post=240"}],"version-history":[{"count":39,"href":"https:\/\/bms.mimsit.net\/dosing\/wp-json\/wp\/v2\/pages\/240\/revisions"}],"predecessor-version":[{"id":1762,"href":"https:\/\/bms.mimsit.net\/dosing\/wp-json\/wp\/v2\/pages\/240\/revisions\/1762"}],"up":[{"embeddable":true,"href":"https:\/\/bms.mimsit.net\/dosing\/wp-json\/wp\/v2\/pages\/231"}],"wp:attachment":[{"href":"https:\/\/bms.mimsit.net\/dosing\/wp-json\/wp\/v2\/media?parent=240"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}